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. 2014 Apr 4;120(13):2006–2015. doi: 10.1002/cncr.28696

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© 2014 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Clinical and TumorGraft data are illustrated for patient POS-1119. (A) Histology of the TumorGraft reveals a dedifferentiated liposarcoma, similar to results from the patient's pathology reports. (B-D) TumorGraft sensitivity testing was performed to determine which drugs would be effective against the patient's tumor. Ruxolitinib, regorafenib, and ifosfamide significantly blocked tumor growth during TumorGraft testing. Asterisks denote significance (a single asterisk indicates P ≤ .05; double asterisks, P ≤ .01; triple asterisks, P ≤ .001). (E) Radiology reports for patient POS-1119 demonstrate a partial response after treatment with ifosfamide.