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. 2015 Jan 13;8:19. doi: 10.1186/s13071-015-0640-9

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© Zhu et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Change of the diameter of egg granulomas, area of collagen deposition and expression of α-SMA. (A) Granuloma diameter. (B) Area of collagen. (C-D) Statistical analysis of images in hematoxylin-eosin staining and sirius red staining by software GraphPad, respectively. (E) Expression of α-SMA was reduced after the anti-parasite treatment of PZQ. (F) Statistical analysis of the expression of α-SMA by software GraphPad. Bar: 100 micrometer. *p < 0.05 vs the control group(without the treatment of PZQ).