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. 2014 Dec 8;15(1):1079. doi: 10.1186/1471-2164-15-1079

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© Lin et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Validation of the integrative analysis for select genes. Three genes with CpG islands were evaluated. Top row is the relationship between array methylation data and Illumina gene expression; middle row provides Pearson correlation of the array methylation data with the pyrosequencing methylation status; and bottom row shows the relationship of methylation status by pyrosequencing with the quantitative real-time PCR results for the expression of these genes.