Table 2.
Characteristics | ICU (n = 59) | Ward (n = 20) | P value* |
---|---|---|---|
Patient demographics | |||
Age group, yr, median (IQR) | 51 (45, 60) | 49 (42, 63) | 0.96 |
Female, n (%) | 28 (47%) | 14 (70%) | 0.12 |
White, n (%) | 34 (58%) | 14 (70%) | 0.43 |
Baseline health status | |||
Comorbidity scores, median (IQR) | |||
Charlson Comorbidity Index at ICU admission | 1 (0, 4) | 2 (1, 6) | 0.22 |
Functional Comorbidity Index at ICU admission | 1 (0, 3) | 2 (1, 3) | 0.65 |
Neurologic disease, n (%) | 9 (47%) | 5 (56%) | 1.00 |
Upper gastrointestinal disease, n (%) | 11 (58%) | 5 (56%) | 1.00 |
ICU characteristics | |||
ICU admission diagnosis, n (%) | 0.85 | ||
Respiratory (including pneumonia) | 32 (54%) | 11 (55%) | |
Nonpulmonary sepsis and infectious disease | 9 (15%) | 4 (20%) | |
Upper gastrointestinal disease | 10 (17%) | 3 (15%) | |
Cardiovascular disease | 1 (2%) | 1 (5%) | |
Trauma | 3 (5%) | 0 (0%) | |
Other | 4 (7%) | 1 (5%) | |
Primary risk factors for ALI | |||
Aspiration, n (%) | 5 (8%) | 3 (15%) | 0.41 |
Pneumonia, n (%) | 30 (51%) | 9 (45%) | 0.80 |
APACHE II score at ICU admission, median (IQR) | 22 (17, 29) | 24 (18, 30) | 0.79 |
SOFA score at ALI onset, median (IQR) | 8 (6, 11) | 8 (5, 10) | 0.24 |
Ever reintubated, n (%) | 10 (17%) | 1 (5%) | 0.27 |
Intubation duration, d, median (IQR) | 8 (7, 11) | 10 (8, 16) | 0.07 |
Organizational characteristics | |||
Medical (vs. surgical) ICU, n (%) | 41 (69%) | 17 (85%) | 0.25 |
Hospital study site, n (%)† | 0.10 | ||
1 | 14 (24%) | 7 (35%) | |
2 | 14 (24%) | 8 (40%) | |
3‡ | 31 (53%) | 5 (25%) |
Definition of abbreviations: ALI = acute lung injury; APACHE II = Acute Physiology and Chronic Health Evaluation II; ICU = intensive care unit; IQR = interquartile range; SOFA = Sequential Organ Failure Assessment.
Wilcoxon rank-sum test, Fisher’s exact test, or χ2 test.
Percentages may not add to 100% due to rounding.
Hospital uses a referral algorithm.