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. 2014 Dec 5;14(12):23248–23268. doi: 10.3390/s141223248

Table 3.

Comparison of the developed toxicity biosensor performance with other reported toxicity biosensor for the determination of Cu(II), Cd(II), Pb(II), Zn(II), Cr(VI), Co(II), Ni(II), Ag(I) and Fe(III) toxicities.

Heavy Metal Biological Component Immobilization Matrix Dynamic Range (μg/L) LOD (μg/L) Time (min) Reference
Cu(II) A. fischeri Alginate microsphere (10.0 − 200.0) 6.4 6 This work
S. cereviceae Agar gel Agarose (3.4 − 26.9) × 104 1.3 × 104 8 [36]
E. coli (Alux) Carbon paste (0.1 − 1.3) × 103 0.1 × 103 90 [19]
Circinella sp. electrode (6.7 − 134.0) 0.1 30 [39]

Cd(II) A. fischeri Alginate microsphere (0.2 − 5.0) × 103 156 6 This work
S. cereviceae Agar gel (4.6 − 45.8) × 103 1.8 x 103 8 [36]
E. coli (Alux) Free culture (0.1 − 1.0) × 102 12 120 [37]

Pb(II) A. fischeri Alginate microsphere (0.5 − 70.0) × 102 47 6 This work
S. cereviceae Agarose (6.9 − 417.0) × 103 2.8 × 103 8 [36]
E. coli (Alux) Free culture (1.0 − 8.0) × 102 12 30 [37]
E. coli GFP Free culture (0.2 − 82.8) × 103 0.2 × 103 720 [14]

Zn(II) A. fischeri Alginate microsphere (0.5 − 7.0) × 102 32 8 This work
E. coli (Alux) Free culture (0.03 − 8.0) × 105 2.6 × 103 120 [37]
E. coli (Alux) Free culture (0.4 − 2.5) × 103 0.4 × 103 120 [38]

Cr(VI) A. fischeri Alginate microsphere (0.1 − 2.0) × 104 1.0 × 103 6 This work
S. cerevisiae Agarose (26 − 104) × 103 10.4 × 103 5 [36]
E. coli (luxAB) Free culture - 2.0 15 [40]
A ferrooxidans Cellulose membrane (0.02 − 118) × 103 18.0 1 [41]

Co(II) A. fischeri Alginate microsphere (2.0 − 50.0) × 103 1.7 × 103 6 This work
R. eutropha Free culture (0.5 − 23.6) × 103 0.5 × 103 30 [42]

Ni(II) A. fischeri Alginate microsphere (5.0 − 70.0) × 103 2.8 × 103 6 This work
R. eutropha Free culture (0.2 − 17.5) × 102 29.0 30 [42]
B. Sphaericus Whatman membrane 2.0 − 40.0 0.02 1.5 [43]

Ag(I) A. fischeri Alginate microsphere (0.2 − 7.0) × 104 1.8 × 103 6 This work
E. coli (lux) Free culture - 17 120 [44]

Fe(III) A. fischeri Alginate microsphere (5.0 − 70.0) × 103 3.1 × 103 6 This work
P fluorescence Control pore glass 3.0 − 200.0 3.0 5 [45]
A ferrooxidans Cellulose membrane (0.22 − 6050) × 102 22.0 1 [41]