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. 2011 Sep 14;31(37):13110–13117. doi: 10.1523/JNEUROSCI.2569-11.2011

Figure 1.

Figure 1.

e-tau in 3-month-old wild-type mice and P301S tau tg mice. A, Tau-5/BT-2 ELISA recognizes recombinant human tau and mouse tau equivalently. n = 4. B, At varying flow rates of the microdialysis perfusion buffer from 0.35 μl/min to 1.5 μl/min, e-tau was quantified by ELISA in the hippocampus in wild-type (WT, n = 12) and P301S tg (P301S tg, n = 7) mice. C, The mean e-tau levels were calculated by the zero flow method. ***p < 0.0001 by unpaired t test. D, ISF (n = 13) and CSF (n = 8) tau levels were measured in 3-month-old wild-type mice. **p < 0.01 by unpaired t test. E, e-tau levels was determined in 3-month-old wild-type mice (WT, n = 5) and tau knock-out mice (Tau KO, n = 5).