Table I.
Descriptive statistics of the main variables concerning patients, primary sites and defects.
| Characteristic | N = 274 |
|---|---|
| Age at diagnosis | |
| Median | 70 |
| Range | 29-92 |
| Sex [N (%)] | |
| Male | 199 (72.6%) |
| Female | 75 (27.4%) |
| Variant (PMMC vs. PMMF) [N (%)] | |
| PMMC | 237 (86.5%) |
| PMMF | 37 (13.5%) |
| Primary site [N (%)] | |
| Larynx and Hypopharynx | 21 (7.7%) |
| Mandible | 19 (7%) |
| Oropharynx | 85 (31%) |
| Skin | 5 (1.8%) |
| Occult primary | 1 (0.3%) |
| Oral cavity | 143 (52.2%) |
| Retromolar | 56 (20.4%) |
| Tongue | 87 (31.8%) |
| Hystotype | N (%) |
| SCC | 255 (93%) |
| Salivary histotypes | 17 (6.2%) |
| Malignant ameloblastoma | 1 (0.4%) |
| Osteosarcoma | 1 (0.4%) |
| Type of defect | |
| Mucosa | 141 (51.5%) |
| Mucosa+bone | 112 (40.9%) |
| Mucosa+skin | 11 (4%) |
| Skin | 10 (3.6%) |
| Previous treatments for HNSCC | |
| None | 209 (76.3%) |
| Radio±chemotherapy | 48 (17.5%) |
| Surgery | 3 (1.1%) |
| Surgery+ radio±chemotherapy | 14 (5.1%) |
| Adjuvant /perioperative treatments | |
| None | 154 (56.2%) |
| Radiotherapy | 102 (37.2%) |
| Brachytherapy | 4 (1.5%) |
| Radio±chemotherapy | 14 (5.1%) |
| Timing | |
| Immediate | 265 (96.7%) |
| Delayed (management of radiotherapy sequelae) | 9 (3.3%) |
| Early and late complications of the procedure | |
| Partial skin necrosis | 8 (2.9%) |
| Total necrosis | 2 (0.7%) |
| Donor site dehiscence | 2 (0.7%) |
| Late hypopharyngeal stricture/ gastrostomy | 1 (0.4%) |
| Death | 1 (0.4%) |
| None | 261 (95.3%) |