Table 3.
Sensitivities for detection of liver cirrhosis by different combinations of non-invasive examinations
|
All patients (n = 182) |
|||||
| Sensitivity | Specificity | PPV | NPV | P value1 | |
| Liver stiffness ≥ 13 kPa and/or ultrasound cirrhosis | 96.1% | 50.5% | 76.5% | 88.5% | |
| Liver stiffness ≥ 13 kPa and/or platelets < 150.000/μL | 93.9% | 49.1% | 75.4% | 82.8% | < 0.0001 |
| Ultrasound and/or platelets < 150.000/μL | 88.2% | 68.0% | 82.6% | 76.9% | < 0.0001 |
| Ultrasound and/or cutaneous liver signs | 87.6% | 62.0% | 79.7% | 74.7% | < 0.0001 |
| Platelets < 150000/μL and/or cutaneous liver signs | 79.4% | 63.7% | 78.5% | 65% | < 0.004 |
1
Sensitivity compared to the combination of liver stiffness and/or ultrasound. NS: Not significant; PPV: Positive predictive value; NPV: Negative predictive value.