Table 4.
≥ 13 kPa (n = 161) | ≥ 27.5 kPa1 (n = 94) | ≥ 54 kPa1 (n = 48) | ≥ 27.5kPa vs < 27.5 kPa P value | ≥ 54 kPa vs < 54 kPa P value | ≥ 54 kPa vs 27.5-54 kPa P value | |
Age, yr | 60 ± 14 | 56 ± 13 | 55 ± 13 | NS | NS | NS |
BMI, kg/m² | 26.2 ± 3.7 | 25.5 ± 4.0 | 24.8 ± 3.7 | NS | 0.05 | NS |
Bilirubin, mg/dL | 1.1 ± 1.0 | 3.2 ± 5.6 | 4.4 ± 6.9 | 0.0001 | 0.007 | 0.04 |
Albumin, g/dL | 3.9 ± 0.4 | 3.4 ± 0.7 | 3.2 ± 0.7 | 0.0001 | 0.0001 | 0.02 |
Immunoglobulins, g/dL | 1.6 ± 0.7 | 2.0 ± 0.7 | 2.1 ± 0.8 | 0.02 | 0.007 | 0.03 |
AST, U/L | 79 ± 49 | 102 ± 71 | 115 ± 83 | 0.02 | 0.015 | 0.07 |
ALT, U/L | 79 ± 56 | 71 ± 51 | 69 ± 54 | NS | NS | NS |
AFP, μg/L2 | 7.6 | 7.7 | 7.8 | NS | NS | NS |
Platelets, 1000/μL | 145 ± 68 | 144 ± 82 | 151 ± 77 | NS | NS | NS |
Prothrombin time, % | 88 ± 13 | 76 ± 19 | 70 ± 18 | 0.0001 | 0.0001 | 0.02 |
APRI-Score3 | 2.4 ± 1.8 | 3.6 ± 3.1 | 4.3 ± 3.6 | 0.03 | NS | NS |
Platelets < 150.000/μL, % | 59.7 | 60.6 | 56.3 | NS | NS | NS |
Ultrasound cirrhosis, % | 73.1 | 88.9 | 93.6 | 0.02 | 0.01 | NS |
Splenomegaly, % | 57.8 | 71.4 | 72.3 | 0.09 | NS | NS |
Ascites, % | 16.4 | 35.5 | 52.1 | 0.01 | 0.0001 | 0.01 |
Cutaneous liver signs, % | 43.3 | 55.3 | 63.2 | NS | 0.09 | NS |
Cut-off values in accordance to Foucher et al[30];
AFP is given as median value;
APRI-Score was only applied to patients with chronic viral hepatitis. NS: Not significant.