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. 2015 Jan 21;21(3):953–960. doi: 10.3748/wjg.v21.i3.953

Table 4.

Comparison of transient elastography with clinical and biochemical parameters

≥ 13 kPa (n = 161) ≥ 27.5 kPa1 (n = 94) ≥ 54 kPa1 (n = 48) ≥ 27.5kPa vs < 27.5 kPa P value ≥ 54 kPa vs < 54 kPa P value ≥ 54 kPa vs 27.5-54 kPa P value
Age, yr 60 ± 14 56 ± 13 55 ± 13 NS NS NS
BMI, kg/m² 26.2 ± 3.7 25.5 ± 4.0 24.8 ± 3.7 NS 0.05 NS
Bilirubin, mg/dL 1.1 ± 1.0 3.2 ± 5.6 4.4 ± 6.9 0.0001 0.007 0.04
Albumin, g/dL 3.9 ± 0.4 3.4 ± 0.7 3.2 ± 0.7 0.0001 0.0001 0.02
Immunoglobulins, g/dL 1.6 ± 0.7 2.0 ± 0.7 2.1 ± 0.8 0.02 0.007 0.03
AST, U/L 79 ± 49 102 ± 71 115 ± 83 0.02 0.015 0.07
ALT, U/L 79 ± 56 71 ± 51 69 ± 54 NS NS NS
AFP, μg/L2 7.6 7.7 7.8 NS NS NS
Platelets, 1000/μL 145 ± 68 144 ± 82 151 ± 77 NS NS NS
Prothrombin time, % 88 ± 13 76 ± 19 70 ± 18 0.0001 0.0001 0.02
APRI-Score3 2.4 ± 1.8 3.6 ± 3.1 4.3 ± 3.6 0.03 NS NS
Platelets < 150.000/μL, % 59.7 60.6 56.3 NS NS NS
Ultrasound cirrhosis, % 73.1 88.9 93.6 0.02 0.01 NS
Splenomegaly, % 57.8 71.4 72.3 0.09 NS NS
Ascites, % 16.4 35.5 52.1 0.01 0.0001 0.01
Cutaneous liver signs, % 43.3 55.3 63.2 NS 0.09 NS
1

Cut-off values in accordance to Foucher et al[30];

2

AFP is given as median value;

3

APRI-Score was only applied to patients with chronic viral hepatitis. NS: Not significant.