Table 1.
Characteristics of 199 patientsa submitted to hepatic resection with curative intent for metastatic colorectal cancer
| Variable | ||
|---|---|---|
| Demographic characteristics | ||
| Gender, male, n (%) | 132 (66%) | |
| Age, years, mean ± SD | 63 ± 11 | |
| Temporal relationship, metachronous, n (%) | 107 (54%) | |
| Colon to hepatic surgery, months, median (IQR) (n = 192) | 12 (5–23) | |
| CEA, μg/l, median (IQR) (n = 159) | 8 (4–27) | |
| Elevated CEA, n (%) | 124 (78%) | |
| Perioperative characteristics | ||
| Resection, major, n (%) | 120 (60%) | |
| Blood loss of >300 ml, n (%) (n = 195) | 68 (35%) | |
| Transfusion, n (%) (n = 189) | 29 (15%) | |
| Pringle duration >15 min, n (%) (n = 145) | 112 (77%) | |
| Operating time, min, median (IQR) (n = 190) | 198 (150–266) | |
| No complications, n (%) | 123 (62%) | |
| Clavien–Dindo grade, n (%) (n = 198) | ||
| Grade I | 17 (9%) | |
| Grade II | 42 (21%) | |
| Grade IIIa | 5 (3%) | |
| Grade IIIb | 3 (2%) | |
| Grade IVa | 2 (1%) | |
| Grade IVb | 1 (1%) | |
| Grade V | 5 (3%) | |
| Primary tumour characteristics | ||
| Location: colon, n (%) | 141 (71%) | |
| Location: rectum, n (%) | 58 (29%) | |
| Primary differentiation, poor, n (%) (n = 181) | 27 (15%) | |
| Lymph node status positive, n (%) (n = 192) | 121 (63%) | |
| Liver metastases characteristics | ||
| Margin, mm, median (IQR) (n = 197) | 3 (1–10) | |
| Margin R1 (0 mm), n (%) | 38 (19%) | |
| Margin <1 mm, n (%) | 22 (11%) | |
| Margin 1–10 mm, n (%) | 94 (48%) | |
| Margin >10 mm, n (%) | 43 (22%) | |
| Number of metastases, median (IQR) (n = 196) | 2 (1–2) | |
| Size of metastases, mm, median (IQR) (n = 195) | 35 (24–57) | |
a
Numbers available for analysis vary as shown.
SD, standard deviation; IQR, interquartile range; CEA, carcinoembryonic antigen.