Table 1.
Group | LNCaP (6 weeks) | PC3 (4 weeks) | ||
---|---|---|---|---|
PSA<25 ng/ml | TV <100 mm3 | Combined | TV <100mm3 | |
Ad-Luc | 31% (5/16) | 25% (4/16) | 25% (4/16) | 30% (3/10) |
Ad-E2F1 | 53% (9/17) | 53% (9/17)‡ | 53% (9/17)‡ | 70% (7/10)‡ |
Ad-Luc+RT | 22% (6/27) | 33% (9/27) | 18% (5/27) | 24% (6/25) |
Ad-E2F1+RT | 85% (23/27)* | 93% (25/27)* | 85% (23/27)* | 68% (17/25)† |
Ad-Luc (pooled)1 | 26% (11/43) | 30% (13/33) | 21% (9/43) | 26% (9/35) |
Ad-E2F1 (pooled)1 | 73% (32/44)† | 77% (34/44)† | 73% (32/44)† | 69% (24/35)† |
Pooled data for the corresponding control (Ad-Luc) and test vector (Ad-E2F1)
p<0.05 compared to all groups above
p<0.05 compared to the group above
p<0.1 compared to the group above