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. 2014 Jul 1;10(7):737. doi: 10.15252/msb.20145243

Figure 6. MinSpan TRN predictions suggest informative dual perturbation experiments that led to discovery of novel Escherichia coli transcriptional regulation.

Figure 6

  1. Nac plays a role in purine metabolism and a larger role in nitrogen metabolism than previously known. Nac also regulates Lrp through gcvB.
  2. Cra regulates tnaCAB, which is also subject to Crp regulation.
  3. MntR plays a regulatory role for four genes that are heavily regulated by ArcA/Fnr/Fur/PdhR and are utilized during anaerobic conditions.