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Immunohistochemical expression of neuroblastoma markers in neuroblastoma PDXs. NCAM was retained in virtually all tumour cells and CHGA, TH and SYP were heterogenously expressed in PDXs. SK-N-BE(2)c orthotopic tumours exhibited very low numbers of CHGA-positive cells and lacked SYP-positive cells. The shown pictures are representative for the mice. Scale bar is 100 µm in the overviews and 50 µm in the close-ups.
