Table 1.
Monoclonal antibodies, isotypes, and tissue specificity
| Clone | Isotype* | Tissue(s) recognized |
|---|---|---|
| 1A10 | IgM | Intestine |
| 1B11 | IgM | Intestine† |
| 1C3 | IgM | Intestine† |
| 1E12 | IgM | Epidermal & intestinal nuclei |
| 1F12 | IgM | CNS neurons (small subset) |
| CNS processes in neuropil (subset) | ||
| PNS processes in neuropil (subset) | ||
| 1H8 | IgM | Nuclei (elevated in CNS) |
| 1H11 | IgM | Cilia† |
| 2C11 | IgG1 | Peripharyngeal secretory cells & projections |
| 2D2 | IgM | CNS neurons (small subset) |
| CNS processes in neuropil (subset) | ||
| PNS processes in neuropil (subset) | ||
| 2E8 | IgM | Pigment cups† |
| 2G4 | IgM | Intestine & epidermis |
| 2H3 | IgM | Muscles |
| 3A4 | IgM | Intestine† |
| 3A10 | IgM | Intestine† |
| 3D4 | IgM | Marginal/anterior secretory cells intestine (weak)† |
| 3D10 | IgM | Ventral puncta† |
| 3F11 | IgG1 | Intestine |
| 3G7 | IgM | Epidermal basement membrane |
| 3G9 | IgM | Intestine |
| 3H3 | IgM | Epidermis, enriched in cell:cell junctions |
| 4D2 | IgM | Intestine |
| 4H4 | IgM | Ventral secretory cells |
| 4H8 | IgM | Epidermal nuclei (subset)† |
*All mAbs possessed kappa light chains.
†Pattern based on primary screen; mAb has not been characterized further.