Table 2.
Control | NO 2.5% | NO 5% | SP 2.5% | SP 5% | |
---|---|---|---|---|---|
SREBP-2 | 1.2 ± 0.1 | 1.5 ± 0.2 | 1.5 ± 0.2 | 1.1 ± 0.2 | 0.9 ± 0.1 |
LDLR | 1.5 ± 0.2ab | 2.1 ± 0.3a | 2.1 ± 0.3a | 1.4 ± 0.2ab | 1.2 ± 0.2b |
HMGR | 1.3 ± 0.2b | 2.7 ± 0.5a | 1.9 ± 0.3ab | 1.3 ± 0.2b | 1.0 ± 0.2b |
SREBP-lc | 1.5 ± 0.2 | 1.6 ± 0.2 | 1.4 ± 0.2 | 1.3 ± 0.3 | 1.1 ± 0.1 |
FAS | 0.8 ± 0.1 | 1.1 ± 0.2 | 0.6 ± 0.1 | 0.7 ± 0.1 | 0.7 ± 0.1 |
ACC-1 | 0.9 ± 0.1b | 1.6 ± 0.3a | 1.4 ± 0.1a | 1.0 ± 0.1b | 0.7 ± 0.1b |
SCD-1 | 1.1 ± 0.2b | 2.6 ± 0.4a | 2.8 ± 0.2a | 1.8 ± 0.2b | 1.4 ± 0.1b |
ACOX-1 | 1.2 ± 0.1b | 2.8 ± 0.6a | 2.5 ± 0.2a | 1.8 ± 0.3ab | 1.6 ± 0.2ab |
CPT-lα | 1.6 ± 0.2b | 3.0 ± 0.4a | 2.9 ± 0.3a | 2.2 ± 0.2ab | 2.1 ± 0.3ab |
Notes. Values are mRNA levels relative to control. Mean ± SEM. n=8 per group.
Values with a different superscript for each gene are significantly different (P < 0.05).