Table 1.
Participant demographic and clinical characteristics
| Alzheimer’s Disease (N=251) | Healthy Controls (N=51) | P-value | |
|---|---|---|---|
| Age, Mean (SD) | 72.0 (8.14) | 63.6 (7.68) | < 0.001 |
| Female, n (%) | 143 (57.0) | 21 (41.2) | 0.039 |
| Primary language, n (%) | 0.0343 | ||
| Simplified Chinese | 123 (49.0) | 18 (35.3) | |
| Traditional Chinese | 57 (22.7) | 17 (33.3) | |
| Korean | 66 (26.3) | 12 (23.5) | |
| English | 5 (2.0) | 4 (7.8) | |
| Education Level, n (%) | 0.0231 | ||
| Elementary School | 74 (29.5) | 5 (9.8) | |
| Middle School | 47 (18.7) | 14 (27.4) | |
| High School | 51 (20.3) | 15 (29.4) | |
| At least some college | 79 (31.5) | 17 (33.3) | |
| Civil Status, n (%) | 0.4652 | ||
| Married | 202 (80.5) | 46 (90.2) | |
| Widowed | 44 (17.5) | 4 (7.8) | |
| Divorced or Separated | 4 (1.6) | 1 (2.0) | |
| Never Married | 1 (0.4) | 0 (0.0) | |
| Domestic Situation, n (%) | 0.178 | ||
| Living with spouse | 176 (70.1) | 41 (80.4) | |
| Living with other family | 64 (25.5) | 10 (19.6) | |
| Living alone | 11 (4.4) | 0 (0.0) | |
| BMI, Mean (SD) | 22.9 (2.33) | 24.6 (3.20) | 0.001 |
| Brain MRI, n (%) | < 0.001 | ||
| Normal | 0 (0.0) | 43 (84.3) | |
| Abnormal, not clinically significant | 146 (58.2) | 8 (15.7) | |
| Abnormal, clinically significant | 101 (40.2) | 0 (0.0) | |
| Missing | 4 (1.6) | 0 (0.0) | |
| CSDD Total, Mean (SD), Median (IQR) | |||
| Informant Score (n=224, 48) | 2.4 (2.49), 2 (4) | 0.6 (1.76), 0 (1) | < 0.001 |
| Participant Score (n=247, 51) | 2.0 (2.40), 1 (3) | 0.8 (1.27), 0 (1) | 0.001 |
| Rater Score (n=236, 51) | 2.0 (2.26), 1 (3) | 0.6 (0.98), 0 (1) | < 0.001 |
| RMHIS Total Score, Mean (SD), Median (IQR) | 0.6 (0.69), 0 (1) | 0.4 (0.53), 0 (1) | 0.075 |