Table 1.
Demographic and neuropsychological data
| Symptomatic carrier (n = 8) | Asymptomatic carrier (n = 3) | Non-carrier (n = 8) | p-value | |
|---|---|---|---|---|
| Age (years) | 50.1 ± 5.4 | 42.55 ± 8.7 | 43.7 ± 12.0 | 0.313 |
| Gender (M, F) | 5, 3 | 0, 3 | 2, 6 | 0.106 |
| Education (years) | 12.75 ± 0.9 | 14.3 ± 2.1 | 13.4 ± 1.3 | 0.764 |
| % APOE ε4+ | 25 | 0 | 62.5 | 0.106 |
| MMSE Total Score | 23.6 ± 5.6 | 28.3 ± 0.6 | 27 ± 1.6 | 0.189 |
| COWA Total Score * | 22.1 ± 10.6 | 33.7 ± 6.7 | 38.86 ± 10 | 0.045*** |
| Block Design Total * | 23.4 ± 12.8 | 33.3 ± 10 | 34.43 ± 4.2 | 0.235 |
| Word List Imm Total ** | 11.75 ± 5.5 | 28 ± 1.4* | 21.9 ± 4.6 | 0.006*** |
| Word List Del Total ** | 2.75 ± 2 | 9.5 ± 0.7* | 8.13 ± 1.6 | < 0.001*** |
M = male; F = female; MMSE = Mini-Mental State Exam; COWA = Controlled Oral Word Association; Word List Imm = CERAD Word List – Immediate Recall; Word List Del = CERAD Word List – Delayed Recall. Mean ± Standard Deviation.
*
Missing one non-carrier.
**
Missing one asymptomatic carrier.
***
Significant at p < 0.05.