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. 2014 Dec 28;14:108. doi: 10.1186/s12896-014-0108-6

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© Klangjorhor et al.; licensee BioMed Central. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Cartilage-specific extracellular matrix production in monolayer cultures and gelatin scaffolds. Human articular chondrocytes were cultured on scaffolds for 21 days and then digested with papain. The papain digests were assayed for cartilage extracellular matrix components including HA (A), s-GAG (B), collagen (C) and uronic acid (D) content. *, # p-values are < 0.05; **, ## p-values are < 0.01; * is a significant amount compared to the PBS control; # is a significant amount compared to the soluble control.