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. Author manuscript; available in PMC: 2015 Jan 20.
Published in final edited form as: JAMA Intern Med. 2014 Aug;174(8):1227–1234. doi: 10.1001/jamainternmed.2014.2894

Table 1.

Base assumptions about key model parameters*

Parameter Value References
Risk of photocoagulation 29% reduction per 0.9% change in A1c 3
Risk of neuropathy 19% reduction per 0.9% change in A1c 3
Risk of microalbuminuria 33% reduction per 0.9% change in A1c 3
Risk of CHD event 15% reduction per 1.0% change in A1c 7–11,29
Utility of visual loss 0.69 (0.40–0.85) 43,44
Utility of ESRD 0.61 (0.40–0.80) 43,68
Utility of Myocardial Infarction 0.88 (0.70 – 0.95) 69
Utility of Stroke 0.64 (0.40–0.85) 70
Utility of amputation 0.60 (0.40 – 0.80) 43,44,68
*

For more detail, see technical report