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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Pac Symp Biocomput. 2015;20:32–43.

Figure 3.

Figure 3

Performance comparison for CCLE pharmacogenomics data. (A) Predictability score with WRMSE metric of LASSO, Ridge, SGSR with KEGG, Biocarta, NCI/Nature, GO-BP and GO-MF pathways using EXP data across the 24 CCLE drugs, (B) Performance discrepancy between benchmarked LASSO, Ridge, and SGSR models with five available pathway databases with EXP; (C) Predictability score with WRMSE metric of LASSO, Ridge, SGSR with KEGG, Biocarta, NCI/Nature, GO-BP and GO-MF pathways with COPY across the 24 CCLE drugs, (D) Performance discrepancy between benchmarked LASSO, Ridge and SGSR models with five available pathway databases using COPY data.