Table 4.

Area Under the Curve and Net Reclassification Index for Cox Regression models of Cardiovascular Disease Endpoints

N = 6,779	C-statistic	P-value*	Net Reclassification Index (95% CI)
CVD
Traditional risk factors alone	0.756	–	–
CAC presence	0.776	<0.001	0.110 (0.060 – 0.159)
Carotid plaque presence	0.760	0.033	0.012 (−0.022 – 0.045)
Mean CCA IMT ≥ 75th percentile	0.757	0.111	−0.007 (−0.031 – 0.018)
Carotid plaque/CIMT75	0.759	0.034	0.008 (−0.020 – 0.035)
CHD
Traditional risk factors alone	0.752	–	–
CAC presence	0.784	<0.001	0.103 (0.052 – 0.155)
Carotid plaque presence	0.757	0.043	0.006 (−0.026 – 0.037)
Mean CCA IMT ≥ 75th percentile	0.754	0.153	−0.005 (−0.031 – 0.022)
Carotid plaque/CIMT75	0.756	0.055	0.012 (−0.016 – 0.039)
Stroke/TIA
Traditional risk factors alone	0.782	–	–
CAC presence	0.785	0.438	0.028 (−0.012 – 0.068)
Carotid plaque presence	0.787	0.045	0.015 (−0.017 – 0.048)
Mean CCA IMT ≥ 75th percentile	0.783	0.160	0.000 (−0.003 – 0.034)
Carotid plaque/CIMT75	0.785	0.450	0.006 (−0.022 – 0.034)

^*Compared to traditional risk factors alone

Abbreviations as in Tables 1.