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2-AG levels are elevated in patients who developed a high level of post-operative pain. PEA, AEA, and 2-AG levels in the (A) serum, (B) CSF, and (C) synovial fluid were examined in patients who developed low (NRS < 5, n = 24) and high (NRS ≥ 5, n = 21) post-operative pain. 2-AG levels were elevated in the CSF and synovial fluid of high pain patients (p < 0.05).
