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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Nat Med. 2014 Oct 5;20(11):1263–1269. doi: 10.1038/nm.3699

Figure 3.

Figure 3

Oral NEN improves glycemic control in db/db mice. (a) Fasting blood glucose concentration of db/db mice fed with either normal chow diet (control), or the same chow diet containing 1,500 ppm NEN (NEN), measured at indicated time points. (b) Basal plasma insulin concentration of the db/db mice as defined in a, measured at indicated time points. (c) Glycated hemoglobin A1c (HbA1c) level of the db/db mice as defined in a, measured at day 60. (d) Body weight of the db/db mice as defined in a, measured at indicated time points. (e) Daily food intake of the db/db mice as defined in a. n = 9 for all groups. Student t-test; *P < 0.05; ***P < 0.001; error bar, s.d.