Table 1.
Descriptive statistics for lesions. STD is standard deviation and IQR is the inter-quartile ratio. De novo lesions were more common than repeat lesions in the RRMS group. The SPMS group had fewer lesions and a more even ratio between de novo and repeat.
| Lesion type | Mean (STD) | Median (IQR) | Mean (STD)/year | Median (IQR)/year | |
|---|---|---|---|---|---|
| RRMS | |||||
| Volume (mm3) |
T2 | 7374 (8729) | 2315 (10,125) | ||
| de novo | 181 (249) | 42 (298) | 2426 (3718) | 710 (2838) | |
| repeat | 43 (72) | 7.9 (50) | 818 (1246) | 252 (878) | |
| Volume (% of T2) |
de novo | 3.5 (5.7) | 1.4 (3.8) | 36 (56) | 18 (34) |
| repeat | 0.64 (1.0) | 0.19 (0.94) | 11 (16) | 0.19 (0.94) | |
| Count | de novo | 5.4 (6.6) | 2.0 (9.0) | 76 (114) | 26 (88) |
| repeat | 2.5 (3.8) | 1.0 (3.0) | 47 (72) | 19 (42) | |
| Volume ratio | de novo : repeat | 11 (22) | 3.2 (9.3) | ||
| Count ratio | 3.5 (5.7) | 1.0 (4.0) | |||
| SPMS | |||||
| Volume (mm3) |
T2 | 10,867 (10,292) | 8201 (11,083) | ||
| de novo | 79.8 (152) | 26 (86) | 411 (670) | 189 (305) | |
| repeat | 95 (126) | 49 (137) | 544 (713) | 251 (438) | |
| Volume (% of T2) |
de novo | 0.91 (2.1) | 0.28 (0.77) | 4.4 (8.8) | 1.6 (3.9) |
| repeat | 0.83 (1.1) | 0.43 (1.1) | 3.9 (6.3) | 2.5 (3.5) | |
| Count | de novo | 2.1 (2.6) | 1.0 (3.0) | 11 (12) | 7.0 (8.6) |
| repeat | 3.4 (4.0) | 2.0 (5.0) | 16 (17) | 10 (17) | |
| Volume ratio | de novo : repeat | 2.3 (4.9) | 0.75 (1.6) | ||
| Count ratio | 0.97 (1.9) | 0.0 (1.0) | |||