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. 2015 Jan 20;10(1):e0115439. doi: 10.1371/journal.pone.0115439

Table 1. Brain and plasma levels of monoamines and their metabolites.

Striatum Hippocampus Prefrontal cortex Plasma
Control 51.13±1.10 32.14±1.67 23.81±0.69 160.45±3.70
DA LPS 80.61±2.79 38.52±1.00 33.26±1.33 213.55±4.51
T-test t(41) = -10.65, p<0.001 t(41) = -3.07, p<0.01 t(41) = -6.68, p<0.001 t(41) = -9.19, p<0.001
Control 15.43±0.50 24.91±0.52 16.03±0.46 7.42±0.19
DOPAC LPS 25.40±1.08 29.30±0.77 22.55±0.78 8.95±0.13
T-test t(41) = -8.97, p<0.001 t(41) = -4.91, p<0.001 t(41) = -7.52, p<0.001 t(41) = -6.39, p<0.001
Control 7.45±0.27 16.81±0.53 14.84±0.69 4.94±0.18
3-MT LPS 4.53±0.17 14.02±0.38 9.28±0.60 7.90±0.30
T-test t(41) = 8.62, p<0.001 t(41) = 4.07, p<0.001 t(41) = 5.91, p<0.001 t(41) = -8.74, p<0.001
Control 12.76±0.38 27.79±1.26 18.77±0.66 5.69±0.28
HVA LPS 21.70±0.69 38.35±1.94 25.73±0.70 9.23±0.24
T-test t(41) = -11.88, p<0.001 t(41) = -4.73, p<0.001 t(41) = -7.19, p<0.001 t(41) = -9.36, p<0.001
Control 24.80±0.77 33.47±1.50 25.30±0.60 46.33±2.04
5-HT LPS 18.62±1.12 22.54±0.90 19.53±0.59 41.89±1.79
T-test t(41) = 4.68, p<0.001 t(41) = 5.84, p<0.001 t(41) = 6.75, p<0.001 t(41) = 1.59, p = 0.12
Control 13.59±0.69 17.51±0.48 22.67±1.00 230.50±3.53
5-HIAA LPS 20.00±0.85 22.96±1.57 30.29±0.98 245.32±2.35
T-test t(41) = -5.91, p<0.001 t(41) = -3.64, p<0.001 t(41) = -5.36, p<0.001 t(41) = -3.30, p<0.01

Values (ng/ml) represent mean ± SEM.