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. Author manuscript; available in PMC: 2015 Jan 20.
Published in final edited form as: Chem Rev. 2014 Mar 24;114(7):3495–3578. doi: 10.1021/cr400458x

Figure 37.

Figure 37

X-ray crystal structure of MID1-zinc, a designed protein with a metal-mediated protein interface. The red mesh represents the active site cleft above the open coordination site of the ZnHis3 metal site. Reproduced with permission from ref 211. Copyright 2012 American Chemical Society.