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. Author manuscript; available in PMC: 2015 Jan 20.
Published in final edited form as: Chem Rev. 2014 Mar 24;114(7):3495–3578. doi: 10.1021/cr400458x

Scheme 7.

Scheme 7

(A) Reduction of Prochiral Imines 9-ox, 10-ox with Subsequent Deracemization of Cyclic Amines; (B) Stereoinversion of Natural Nicotine (S)-11-red to (R)-11-red, Leading to the Formation of the Chiral Alcohol 11-redol; (C) Formation of L-Pipecolic Acid (13) from L-Lys (12); and (D) Hydroxylation of 2-Hydroxybiphenyl (14) Coupled to an ATHase-Catalyzed NADH Regeneration Processa

aMAO-N, a monoamine oxidase; ATHase, an artificial transfer hydrogenase varian; LAAO, L-amino acid oxidase; DAAO, D-amino acid oxidase; HbpA, 2-hydroxybiphenyl monooxygenase. Reproduced with permission from ref 555. Copyright 2013 Nature Publishing Group.