Table 1.

Regions of interest exhibiting activation differences between conflict, approach‐reward, and avoid‐threat decision trials of the AAC

Side	Region	BA	Cluster size (mm3)	x a	y	z	F b	Direction
Right	Dorsal ACCc	32	4032	5	30	27	8.73	CONF > AV > APP
Right	Middle frontal/precentral gyrus	6	896	40	−3	47	7.75	[CONF = AV] > APP
Right	dlPFC	9,6	448	51	6	37	7.58	CONF > AV > APP
Right	dlPFC	9	384	43	33	33	6.98	CONF > APP > AV
Right	Anterior insula, inferior frontal gyrus	13, 47	2752	37	18	3	9.10	CONF > AV > APP
Left	Anterior insula, inferior frontal gyrus	13, 47	832	−35	20	2	8.21	CONF > [AV = APP]
Right	Caudate body		320	10	5	11	7.48	[CONF = AV] > APP
Left	Caudate head		192	−9	7	3	9.33	CONF > [AV = APP]
Left	Posterior insula, superior temporal	13	512	−42	−21	19	7.45	AV > CONF > APP
Left	Dorsal cingulate, medial frontal	24, 6	448	−8	−5	48	7.18	[AV = APP] > CONF
Right	Posterior insula, superior temporal	13	384	44	−16	8	11.66	AV > CONF > APP
Right	Posterior insula	13	384	39	−13	18	6.69	[AV = APP] > CONF
Left	Middle frontal/precentral gyrus	6	448	−24	19	53	7.07	[AV = APP] > CONF

^aAll coordinates are Talairach coordinates (x,y,z) based on Talairach Daemon software (Lancaster, et al., 2000).

^bResults shown from ANOVA analysis examining effect of condition (conflict, approach‐reward, avoid‐threat) on percent signal change during decision trials of the AAC task (for N = 15 healthy controls). Clusters listed met significance cutoff of P < 0.01, Monte Carlo adjusted for multiple comparisons within small volume regions of interest. Direction of findings was identified using post‐hoc paired samples t‐tests.

^cAbbreviations: BA = Brodmann area; ACC = anterior cingulate cortex; CONF = conflict decision trials; AV = avoid‐threat decision trials; APP = approach‐reward decision trials; mm³ = millimeters cubed.