Table 1.
Characteristics of donors
| SF-36 Data (N=374) | No SF-36 Data (N=84) | |||
|---|---|---|---|---|
| N or Mean, SD | Percent or Range | N or Mean, SD | Percent or Range | |
| Race | ||||
| American Indian or Alaska Native | 2 | 0.5 | 0 | 0.0 |
| Asian | 8 | 2.1 | 2 | 2.4 |
| Black/African American | 9 | 2.4 | 3 | 3.6 |
| Native Hawaiian or Other Pacific Islander | 1 | 0.3 | 1 | 1.2 |
| White | 349 | 93.3 | 73 | 86.9 |
| More than One Race | 5 | 1.3 | 5 | 6.0 |
| Ethnicity § | ||||
| Hispanic/Latino | 46 | 12.3 | 18 | 21.4 |
| Not Hispanic/Latino | 328 | 87.7 | 66 | 78.6 |
| Sex | ||||
| Male | 174 | 46.5 | 42 | 50.0 |
| Female | 200 | 53.5 | 42 | 50.0 |
| Age at evaluation for donation | 38.0, 10.2 | 18.2 – 62.7 | 36.6, 10.7 | 18.8 – 54.6 |
| BMI at evaluation for donation | 26.2, 4.0 | 16.4 – 42.4 | 26.6, 3.4 | 20.4 – 34.7 |
| Relationship to recipient | ||||
| Biological | 233 | 62.3 | 56 | 66.7 |
| Non-biological | 97 | 25.9 | 19 | 22.6 |
| Spouse | 44 | 11.8 | 9 | 10.7 |
| Education attainment at evaluation for donation§ | ||||
| Bachelor’s degree or higher | 161 | 43.0 | 22 | 26.2 |
| Less than a bachelor’s degree | 177 | 47.3 | 51 | 60.7 |
| Missing | 36 | 9.6 | 11 | 13.1 |
| Current smoker | 37 | 9.9 | 13 | 15.5 |
| Previous smoker | 59 | 15.8 | 15 | 17.9 |
| History of depression | 29 | 7.8 | 2 | 2.4 |
| Systemic hypertension | 9 | 2.4 | 2 | 2.4 |
| Patient reports pain drug use | 70 | 18.7 | 12 | 14.3 |
| Non-prescription drug use | 66 | 17.6 | 10 | 11.9 |
| Prescription drug use | 7 | 1.9 | 2 | 2.4 |
| Complication occurred before study end point* | ||||
| Any grade | 159 | 42.5 | 36 | 42.9 |
| Grade 1 α | 57 | 15.2 | 11 | 13.1 |
| Grade 2 α | 95 | 25.4 | 23 | 27.4 |
| Grade 3 α | 2 | 0.5 | 1 | 1.2 |
| SF-36 Data (N=374) | No SF-36 Data (N=84) | |||
| N or Mean, SD | Percent or Range | N or Mean, SD | Percent or Range | |
|
Complication occurred before last SF-36 time
period |
147 | 39.3 | -- | -- |
| Grade 1 α | 51 | 13.6 | -- | -- |
| Grade 2 α | 90 | 24.1 | -- | -- |
| Grade 3 α | 2 | 0.5 | -- | -- |
| Recipient graft failure before study end point* | 109 | 29.1 | 33 | 39.3 |
| Recipient graft failure before or during last donor SF-36 time period† |
105 | 28.1 | -- | -- |
| Recipient death before study end point* | 82 | 21.9 | 22 | 26.2 |
| Recipient death before or during last donor SF-36 time period† Enrolled in A2ALL study before donation § |
57 219 |
15.2 58.6 |
-- 30 |
-- 35.7 |
§
P-value < 0.05. Ethnicity (Chi-square test, p=0.03), education (Chi-square test, p=0.02), consented to A2ALL study before donation (Chi-square test, p=0.0001)
α
Complication grade not collected after August 31, 2010
*
Recipient graft failure/death occurred before the end of the A2ALL Cohort study
†
Recipient graft failure/death occurred before the donor’s last SF-36 form was completed