Table 3.
Brain regions showing a significant negative relationship between seed-based functional connectivity and age; regression, at voxel p<0.001 uncorrected and cluster-level p<0.05, FWE corrected.
| Seed ROI | Cluster Size (mm3) | z-score | MNI Coordinates (mm)
|
Identified Region | ||
|---|---|---|---|---|---|---|
| X | Y | Z | ||||
| Caudate Head | 5562 | 4.11 | 9 | −73 | −11 | Calcarine Sulcus |
|
| ||||||
| Caudate Body | N/A | |||||
|
| ||||||
| Anterior Putamen | 5481 | 3.87 | −21 | −94 | 25 | SOG |
|
| ||||||
| Posterior Putamen | 7587 | 4.56 | 6 | −91 | 31 | SOG |
| 8856 | 4.06 | −33 | −25 | 73 | L Somatomotor | |
|
| ||||||
| Pallidum | 8424 | 4.68 | −36 | 41 | 4 | lOFC/vlPFC |
| 13311 | 4.39 | −33 | −25 | 70 | L Somatomotor | |
|
| ||||||
| VTA/SN | 7749 | 4.29 | −51 | −16 | 49 | L Somatomotor |
Note: L = Left; lOFC = Lateral Orbitofrontal Cortex/Ventrolateral Prefrontal Cortex; SOG = Superior Occipital Gyrus