. 2015 Feb;94(2):362–370. doi: 10.1177/0022034514561658

Table.

Mice With Metabolic Syndrome Have Increased Periodontal Expression of Inflammatory Cytokines.

Mice	IL-6	M-CSF	MCP-1	RANKL
Non-MetS
With PBS	0.18 (0.10, 1.59)	0.69 (0.01, 1.68)	0.04 (0.01, 0.23)	1.38 (0.27, 3.30)
With LPS	0.82 (0.10, 1.98)^a	1.15 (0.40, 1.85)^a	0.11 (0.03, 0.37)^a	2.52 (0.55, 3.66)^a
MetS
With PBS	0.73 (0.26, 1.96)^b	1.59 (0.92, 2.99)^b	0.42 (0.02, 1.28)^b	2.10 (0.74, 4.74)^b
With LPS	1.09 (0.39, 2.61)^c	2.69 (1.57, 5.52)^c	1.20 (0.58, 4.58)^c	3.43 (1.19, 7.23)^c

Data are median (minimum, maximum) (n = 7). Mann-Whitney test was performed for statistical analysis.

IL-6, interleukin 6; LPS, lipopolysaccharide; MCP-1, monocyte chemoattractant protein 1; M-CSF, macrophage colony-stimulating factor; PBS, phosphate-buffered saline; RANKL, receptor activator of nuclear factor kappa-B ligand.

P < 0.01 vs. non-MetS mice with PBS injection.

P < 0.01 vs. non-MetS mice with PBS injection. P < 0.05 vs. non-MetS mice with LPS. P < 0.05 vs. MetS mice with PBS.