Table 4.
Studies Comparing Technique Survival and All-Cause Mortality in CAPD and APD
| Study (Year) | Study Design | Setting | Data Source | N (CAPD, APD) | F/U | Outcome |
|---|---|---|---|---|---|---|
| de Fijter et al19 (1994) | RCT | Netherlands (1988–1991) | Single center | 82 (41, 41) | 24 mo | No significant difference in technique survival or all-cause mortality |
| Mujais & Story51 (2006) | Post hoc analysis of prospectively collected data | US (2000–2003) | Multicenter, Baxter Healthcare Corporation On-Call system | 909 (40, 869) | — | Better technique survival in APD (mostly concentrated in the first y of therapy); no difference in all-cause mortality |
| Badve et al52 (2008) | National registry data | Australia & New Zealand (1999–2004) | Multicenter, ANZDATA registry | 4,128 (2,393, 1,735) | 5 y | No significant difference in technique survival or all-cause mortality |
| Sanchez et al53 (2008) | Retrospective study | Mexico (2003–2005) | Single center | 237 (139, 98) | 2 y | In APD, better technique survival and significantly lower all-cause mortality |
| Mehrotra et al4 (2009) | National registry data | US (1996–2004) | Multicenter, USRDS | 66,381 (42,942, 23,439) | 2–10 y | No significant difference in technique survival or all-cause mortality |
| Michels et al54 (2009) | Retrospective study | Netherlands (1997–2006) | Multicenter, NECOSAD | 649 (562, 87) | 5 y | No significant difference in technique survival or all-cause mortality |
| Johnson et al55 (2010) | National registry data | Australia & New Zealand (1999–2004) | Multicenter, ANZDATA registry | 628 high transporters (142, 486); 196 low transportersa | 3 mo-10 y | Compared APD vs CAPD in high transporters and low transporters; no significant difference in technique survival; lower death risk in high transporters treated with APD and higher death risk in low transporters treated with APD |
| Cnossen et al29 (2011) | Retrospective study | US (2001–2008) | Multicenter, Renal Research Institute | 620 (179, 441) | 3 mo-7 y | In APD, significantly better technique survival; no significant difference in all-cause mortality |
| Sun et al56 (2011) | Retrospective study | Taiwan (1997–2008) | Single center | 282 (121, 161) | 3 mo-10 y | In APD, higher technique survival and lower all-cause mortality; for individuals > 65 y old, APD associated with higher mortality |
Abbreviations: ANZDATA, Australia and New Zealand Dialysis and Transplant; APD, automated peritoneal dialysis; CAPD, continuous ambulatory peritoneal dialysis; F/U, follow-up; NECOSAD, Netherlands Cooperative Study on the Adequacy of Dialysis; RCT, randomized controlled trial; USRDS, US Renal Disease System.
a
Number of patients receiving APD vs APD not specified for low transporters.