Small NMDAR EPSCs reduced by XCAR. a, Small EPSC curtailed by XCAR. b, Effect of XCAR on small EPSCs in 9 cells. c, Small EPSC recorded 5–10 minutes (CTL, black) versus 17–22 minutes after breakthrough (Delay, red). d, Peak EPSC in 5 delay experiments. e, XCAR had no effect on AMPAR peak EPSC (no DNQX, VH = −70 mV). f, Effect of XCAR on peak of small, AMPAR EPSCs in 5 cells. VH = +50 mV for a–d. Calibration: 20 pA/20 ms (a,c), 20 pA/10 ms (e).