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. 2014 Sep 15;76(12):1563–1568. doi: 10.1292/jvms.13-0537

Fig. 2.

Fig. 2.

Morphological changes of the D-17 cell line after treating with 0, 10 and 100 µM of loperamide for 24 hr. Cell morphology changed from an attached spindle-shaped appearance (control) to detached and rounded with increasing doses of loperamide. This is a representative cell line, as all others showed similar changes.