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. 2014 Sep 15;76(12):1563–1568. doi: 10.1292/jvms.13-0537

Table 3. Percentage of cells in G0/G1 following incubation with loperamide.

CTAC D-17 CML-1 CMT-12
6 hr
0 µM 48.5 ± 3.1 45.8 ± 1.2 54.6 ± 0.3 49.7 ± 1.4
10 µM 50 ± 2 44.5 ± 0.5 55.8 ± 1.2 51.5 ± 2
30 µM 41.3 ± 1.1 44.8 ± 0.6 59.7 ± 1.3 49 ± 2.3
24 hr
0 µM 38.1 ± 3.3 52.6 ± 1.5 50.6 ± 0.3 58.7 ± 1
10 µM 53.5 ± 2.1 55.5 ± 2.2 57.2 ± 1.6 59.6 ± 0.2
30 µM 56.8 ± 0.8* 63.4 ± 3.7* 70 ± 1.9* 78.2 ± 2.4*
48 hr
0 µM 52.7 ± 5.1 54.4 ± 1.2 49.7 ± 3.1 80.4 ± 1.1
10 µM 51.2 ± 1.6 60.7 ± 1.8 50.3 ± 1.8 77.6 ± 2
30 µM 62.8 ± 2.4* 78.8 ± 1.1* 71.6 ± 0.8* 85.7 ± 1.7*

Percentage of cells in G0/G1 at three different time points and three different loperamide concentrations. Values are expressed as mean ± SEM from three independent experiments. An * indicates that there are significantly more G0/G1 cells compared to the control (0 µM of drug) as analyzed via ANOVA with Tukey post-hoc test.