Table 2.
Comparative antiplatelet effect of ticagrelor 180 mg LD compared with clopidogrel 600 mg LD in Hispanic subjects with CAD
| Timepoint | Ticagrelor 180 mg LD | Clopidogrel 600 mg LD | LS means difference | P value |
|---|---|---|---|---|
| Primary endpoint | ||||
| 2 h post-LD (95 % CI) | 34 (12, 56) | 201 (179, 224) | −167 (−197, −137) | <0.001 |
| Secondary endpoints | ||||
| 0.5 h post-LD (95 % CI) | 135 (105, 164) | 270 (239, 301) | −135 (−172, −98.0) | <0.001 |
| 8 h post-LD (95 % CI) | 34 (9, 59) | 203 (177, 229) | −169 (−204, −134) | <0.001 |
All measurements are in PRU
CAD coronary artery disease, CI confidence interval, LD loading dose, LS least squares, PRU P2Y12 reaction unit