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. 2014 Sep 5;32(2):516–527. doi: 10.1007/s11095-014-1481-5

Table I.

Hydrodynamic Particle Diameter of Solutions of Solutol® HS15 in Filtered Deionised Water, in HBSS:HEPES (25 mM) and in Phosphate Buffer Saline (PBS). Dynamic Light Scattering Measurements Performed at 4, 25 and 37°C. Values Presented As Mean Hydrodynamic Diameter ± SD, n = 4

Concentration
(mM)
Temperature Average hydrodynamic diameter ± SD (nm)
Deionised water HBSS:HEPES PBS
0.10 4°C 11.8 ± 2.2 11.1 ± 3.9 14.6 ± 2.8
25°C 12.8 ± 3.2 13.1 ± 2.9 12.9 ± 1.9
37°C 13.8 ± 4.6 12.9 ± 3.2 12.9 ± 4.1
1.00 4°C 12.9 ± 3.7 12.1 ± 3.9 13.8 ± 3.1
25°C 13.6 ± 3.9 13.1 ± 3.8 13.2 ± 3.1
37°C 14.4 ± 4.8 13.2 ± 3.1 14.6 ± 4.9
10.40 4°C 14.5 ± 4.9 13.8 ± 2.4 13.5 ± 4.0
25°C 12.9 ± 4.1 13.8 ± 3.4 13.1 ± 3.8
37°C 13.6 ± 4.5 13.8 ± 3.9 14.1 ± 3.9
104.00 4°C 13.7 ± 2.5 13.8 ± 3.9 12.9 ± 3.2
25°C 12.9 ± 3.9 12.8 ± 2.9 13.5 ± 3.2
37°C 13.8 ± 3.3 13.6 ± 4.2 13.1 ± 2.6