Table II.
Concentration (mM) |
Papp at 37°C (×10−6 cm/s) |
Papp at 4°C (×10−6 cm/s) |
---|---|---|
Control | 2.27 ± 0.44 | 0.26 ± 0.04 |
0.01 | 2.41 ± 0.52 | 0.25 ± 0.02 |
0.10 | 2.61 ± 0.20 | 0.26 ± 0.016 |
0.52 | 3.01 ± 0.6 (*) | 0.25 ± 0.04 |
1.00 | 4.09 ± 1.21 (**) | 0.26 ± 0.07 |
5.20 | 6.08 ± 1.93 (***) | 0.26 ± 0.02 |
Permeability expressed as mean Papp, values ± SD (N = 3, n = 4). * P = 0.01 , ** P = 0.0021 and *** P = 0.0001