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. 2014 Sep 5;32(2):516–527. doi: 10.1007/s11095-014-1481-5

Table II.

Apical to Basolateral Permeability of FITC-Insulin in the Presence Of Increasing Concentrations of Solutol® HS15 Across Polarised Calu-3 Cell Monolayer Performed at 37°C and 4°C

Concentration
(mM)
Papp at 37°C
(×10−6 cm/s)
Papp at 4°C
(×10−6 cm/s)
Control 2.27 ± 0.44 0.26 ± 0.04
0.01 2.41 ± 0.52 0.25 ± 0.02
0.10 2.61 ± 0.20 0.26 ± 0.016
0.52 3.01 ± 0.6 (*) 0.25 ± 0.04
1.00 4.09 ± 1.21 (**) 0.26 ± 0.07
5.20 6.08 ± 1.93 (***) 0.26 ± 0.02

Permeability expressed as mean Papp, values ± SD (N = 3, n = 4). * P = 0.01 , ** P = 0.0021 and *** P = 0.0001