Fig. 5.

Representative families of current traces recorded from single HeLa cells transfected with vector alone (a), wild-type rat Cx46 (b), or T19M (c). Families of current traces were recorded in response to a series of voltage clamp steps between −60 and 50 mV in increments of 10 mV from a holding potential of −60 mV. Dashed line indicates zero current level. d Average steady-state I–V relationships for vector alone (open squares, n = 5), wild-type (solid circles, n = 4), and T19M (open triangles, n = 3)