Table 1.
Control group | ||||||
---|---|---|---|---|---|---|
Animal # | HR (ms) | PQ (ms) | QTc (ms) | Induction parameter S1-S5 (ms) | ERP (ms) | Inducibility of VF |
1 | 89 (88; 91) | 114 (113; 117) | 361 (357; 364) | 400/200/140/110/100 | 166 | 3/3 |
2 | 94 (93; 94) | 118 (116; 118) | 359 (356; 360) | 350/150/110 | 140 | 3/3 |
3 | 96 (96; 98) | 120 (116; 123) | 438 (436; 444) | 350/160/120/90 | 163 | 3/3 |
4 | 72 (72; 73) | 113 (113; 113) | 368 (367; 368) | 350/140/60 | 130 | 3/3 |
5 | 95 (95; 95) | 110 (108; 110) | 353 (351; 355) | 350/150/140 | 140 | 3/3 |
6 | 68 (67; 68) | 143 (140; 144) | 328 (326; 332) | 300/120/60 | 128 | 3/3 |
Total | 93 (72; 95) | 115 (113; 120) | 386 (356; 437) | 140 (133; 150) | 18/18 (100%) | |
RDN group | ||||||
Animal # | HR (ms) | PQ (ms) | QTc (ms) | Induction parameter S1-S5 (ms) | ERP (ms) | Inducibility of VF |
1 | 78 (78; 79) | 123 (120; 124) | 386 (383; 391) | 400/190/170 | 166 | 3/3 |
2 | 81 (78; 85) | 146 (143; 148) | 389 (382; 400) | 400/170/140 | 149 | 3/3 |
3 | 88 (87; 89) | 149 (145; 153) | 472 (466; 475) | 350/200/80 | 190 | 3/3 |
4 | 49 (48; 49) | 161 (158; 163) | 356 (354; 358) | 400/200/160 | 166 | 3/3 |
5 | 113 (113; 113) | 131 (128; 133) | 421 (416; 425) | 350/180/100 | 170 | 3/3 |
6 | 58 (58; 59) | 153 (150; 155) | 405 (402; 407) | 350/160/140 | 150 | 3/3 |
Total | 79 (58; 88) ** | 145 (133; 153) *** | 402 (382; 422) NS | 159 (150; 169) ** | 18/18 (100%) |
Induction parameters represent minimal cycle lengths of basic stimuli and up to five extrastimuli (S1-5). In each animal was EP protocol made three times. HR indicates heart rate; ERP, effective refractory period of ventricles; VF, ventricular fibrillation; NS,statistically non-significant; **P < 0.01; P ***P < 0.0001.