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Regulatory pathways involving HCMV, miR-21, and Cdc25a. (A) HCMV proteins downregulate miR-21, relieving miR-21-mediated repression of Cdc25a, which promotes replication of HCMV. (B) Overexpression of miR-21 reduces Cdc25a levels, which impairs replication of HCMV.
