FIG 2.

Overall immunogenicity of vaccination with whole-protein versus conserved-region sequences. The frequencies of HIV-1-specific responses in the memory CD4⁺ and CD8⁺ T lymphocyte compartments were plotted for WPV and CRV. The open triangles at the x axis indicate times of DNA prime vaccinations, and the closed triangles indicate times of rAd5 booster vaccinations. For the WPV, open triangles show data for animal 19798, open squares are for animal 20252, and open circles are for animal 21894. For the CRV, open triangles show data for animal 19825, open squares are for animal 20175, and open circles are for animal 21927. The solid lines indicate means for the three animals in each vaccine group.