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. 2014 Oct 22;89(2):908–916. doi: 10.1128/JVI.02933-14

TABLE 2.

Engineered viruses are less virulent than CVB3-WT and CVB-CON

Virus LD50 (PFU)a
CVB3-WT 1 × 105
CVB-CON 1 × 105
CVB-206T 1 × 106
CVB-3*T 5 × 106
a

LD50 values were calculated for each virus in BALB/c mice using the Reed and Muench method.