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Locations of the A204E and G312V mutations in the context of the structure of the Env trimer. (A) Side view of two gp120 subunits of the BG505 SOSIP structure (44) with the A204 residue highlighted in yellow and the G312 residue in red (obtained with MacPyMOL). (B) Top view of all three protomers of the BG505 SOSIP structure with the A204 and G312 residues highlighted.
