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. 2014 Dec 15;5(1):168–179.

Figure 2.

Figure 2

Determination of the appropriate concentrations of bisphosphonates and statins that are not cytotoxic to IM9 cells and ARH77 cells. IM9 cells (A-D) and ARH77 cells (E-H) were incubated in 96-well plates for 24 h and then treated with various concentrations of (A, E) minodronate, (B, F) alendronate, (C, G) fluvastatin, or (D, H) simvastatin. After 5 days, cell viability was quantified by trypan blue dye assays. The results are representative of 5 independent experiments. *p < 0.01 vs. the controls (ANOVA with Dunnet’s test).