Table 1.
List of miRNA signatures for each astrocytoma grade
| A. MiRNAs Signature in Grade II | |||||
|
| |||||
| Probeset ID | P-value | Fold-Change | Probeset ID | P-value | Fold-Change |
|
| |||||
| hsa-miR-1469 | 0.0016 | -4.41 | hsa-miR-30c-2-star | 0.0153 | 2.83 |
| hsa-miR-1308 | 0.0065 | -3.85 | hsa-miR-181a-star | 0.0087 | 2.97 |
| hsa-miR-762 | 0.0091 | -3.15 | hsa-miR-4260 | 0.0126 | 3.01 |
| hsa-miR-92b-star | 0.0021 | -2.97 | hsa-miR-18a | 0.0083 | 3.27 |
| hsa-miR-3196 | 0.0120 | -2.59 | hsa-miR-194 | 0.0103 | 3.29 |
| hsa-miR-149-star | 0.0169 | -2.19 | hsa-miR-99b-star | 0.0181 | 3.46 |
| hsa-miR-768-3p | 0.0103 | 2.05 | hsa-miR-25 | 0.0494 | 3.56 |
| hsa-miR-29c | 0.0405 | 2.06 | hsa-miR-500 | 0.0008 | 3.92 |
| hsa-miR-542-3p | 0.0202 | 2.09 | hsa-miR-15a | 0.0222 | 4.26 |
| hsa-miR-363 | 0.0092 | 2.11 | hsa-miR-489 | 0.0026 | 4.31 |
| hsa-miR-505-star | 0.0067 | 2.14 | hsa-miR-362-5p | 0.0045 | 4.50 |
| hsa-miR-17-star | 0.0225 | 2.21 | hsa-miR-500-star | 0.0001 | 4.57 |
| hsa-miR-20a | 0.0313 | 2.30 | hsa-miR-30b | 0.0306 | 4.88 |
| hsa-miR-125a-3p | 0.0082 | 2.36 | hsa-miR-335 | 0.0460 | 5.15 |
| hsa-miR-664-star | 0.0271 | 2.38 | hsa-miR-371-5p | 0.0196 | 5.42 |
| hsa-miR-30e | 0.0458 | 2.42 | hsa-miR-181c-star | 0.0102 | 5.44 |
| hsa-miR-28-5p | 0.0454 | 2.49 | hsa-miR-339-3p | 0.0038 | 6.24 |
| hsa-miR-4299 | 0.0405 | 2.65 | hsa-miR-532-5p | 0.0012 | 7.49 |
| hsa-miR-339-5p | 0.0485 | 2.77 | hsa-miR-19b | 0.0005 | 9.89 |
| hsa-miR-501-3p | 0.0023 | 2.82 | hsa-miR-497 | 0.0065 | 15.31 |
|
| |||||
| B. MiRNAs Signature in Grade III | |||||
|
| |||||
| Probeset ID | P-value | Fold-Change | |||
|
| |||||
| hsa-miR-487b | 0.0121 | -5.40 | |||
| hsa-miR-222 | 0.0384 | -4.27 | |||
| hsa-miR-126 | 0.0354 | -3.74 | |||
| hsa-miR-1979 | 0.0436 | -2.96 | |||
| hsa-miR-382 | 0.0472 | -2.87 | |||
| hsa-miR-409-3p | 0.0105 | -2.57 | |||
| hsa-miR-1826 | 0.0281 | -2.55 | |||
| hsa-miR-1909 | 0.0115 | -2.43 | |||
| hsa-miR-23b | 0.0166 | -2.09 | |||
| hsa-miR-3197 | 0.0499 | -2.01 | |||
| hsa-miR-1275 | 0.0165 | 2.00 | |||
| hsa-miR-4289 | 0.0067 | 2.01 | |||
| hp_hsa-mir-520h | 0.0419 | 2.13 | |||
| hsa-miR-455-3p | 0.0428 | 2.39 | |||
| hsa-miR-9 | 0.0320 | 2.53 | |||
| hsa-miR-423-5p | 0.0004 | 3.36 | |||
| hsa-miR-3201 | 0.0037 | 6.46 | |||
|
| |||||
| C. MiRNAs Signature in Grade IV | |||||
|
| |||||
| Probeset ID | P-value | Fold-Change | |||
|
| |||||
| hsa-miR-124 | 0.0127 | -46.60 | |||
| hp_hsa-mir-124-2 | 0.0092 | -28.79 | |||
| hp_hsa-mir-124-3 | 0.0086 | -28.76 | |||
| hp_hsa-mir-124-1 | 0.0091 | -28.17 | |||
| hsa-miR-139-5p | 0.0169 | -8.36 | |||
| hsa-miR-330-3p | 0.0047 | -6.03 | |||
| hsa-miR-29a | 0.0098 | -3.58 | |||
| hsa-miR-139-3p | 0.0470 | -3.55 | |||
| hsa-miR-4270 | 0.0279 | -3.18 | |||
| hsa-miR-423-3p | 0.0057 | 2.41 | |||
| hsa-miR-99a | 0.0011 | 3.19 | |||
| hp_hsa-mir-886 | 0.0107 | 3.40 | |||
| hsa-miR-193b | 0.0198 | 3.44 | |||
| hsa-miR-720 | 0.0074 | 4.07 | |||
| hsa-miR-106b | 0.0010 | 4.77 | |||
| hsa-miR-27a | 0.0257 | 4.79 | |||
| hsa-miR-34a | 0.0228 | 4.82 | |||
| hsa-miR-886-3p | 0.0433 | 5.44 | |||
| hsa-miR-1274b | 0.0086 | 7.52 | |||
| hsa-miR-210 | 0.0082 | 8.70 | |||