Figure 4.

Histological analysis of anti-glioma activities of ADS-I wafer implants. Four tumor tissues were randomly selected from each group at day 14 (after MRI imaging analysis). After paraformaldehyde fixing and paraffin embedding, the sections were stained with H&E for histological examination of cell and tissue morphology and structures (upper and middle panels). Data are a typical microscopic imaging of tumor tissue sections under original magnification of both ×200 and ×400. Nuclei: blue, cytoplasm: pink. Apoptotic cells in tissues sections were detected using TUNEL assay (lower panel). Data are a typical fluorescent microscopic imaging of tumor tissue sections under original magnification of ×400. Nuclei: blue, apoptosis cells: green.