Table 4.
Cox-regression analysis reveals that overexpression of four or more MCMs poses a significantly higher hazard ratio than that posed in patients overexpressing three or fewer MCMs
| A. Cox-regression analysis | |||
|
| |||
| Factor | Hazard Ratio | 95% CI | P value |
|
| |||
| MCMs overexpression | |||
| 0 MCM | Reference | ||
| 1 MCMs | 1.22 | 0.89-1.67 | 0.216 |
| 2 MCMs | 1.09 | 0.77-1.54 | 0.610 |
| 3 MCMs | 1.35 | 0.96-1.90 | 0.082 |
| 4 MCMs | 1.84 | 1.35-2.52 | < 0.001 |
| 5 MCMs | 1.72 | 1.26-2.34 | 0.001 |
| 6 MCMs | 1.75 | 1.31-2.34 | < 0.001 |
|
| |||
| B. P value for inclusion in the multivariate Cox-regression analysis | |||
|
| |||
| Factor | P-value for inclusion | ||
|
| |||
| MCM2 | 0.061 | ||
| MCM3 | 0.198 | ||
| MCM4 | 0.881 | ||
| MCM5 | 0.398 | ||
| MCM6 | 0.308 | ||
| MCM7 | 0.641 | ||