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. 2014 Nov 19;89(3):1564–1578. doi: 10.1128/JVI.01536-14

FIG 6.

FIG 6

Expression of chemokine and chemokine receptor mRNA in the lungs of mice with FI-RSV vaccine-enhanced disease. Shown are CCR3 (A), RANTES (B), and TARC (C) mRNA levels. Cytokine mRNA levels were determined by quantitative RT-PCR, and the data were normalized with β-actin. The data are expressed as fold change, with values from control untreated (unimmunized and uninfected) WT mice defined as 1, as indicated by the dashed lines. Unimmunized WT, Eot−/−, IL-5−/−, EotIL-5−/−, and IL-5Tg mice challenged with RSV were included as controls. The data are shown as means and SEM; n = 6. *, P < 0.05 compared with WT FI-RSV-immunized mice challenged with RSV; **, P < 0.05 compared with IL-5Tg FI-RSV-immunized mice challenged with RSV; #, P < 0.05 compared with WT unimmunized and RSV-infected mice; ##, P < 0.05 compared with IL-5Tg unimmunized and RSV-infected mice. The data shown are representative of two separate experiments.