FIG 4.

C-capsids confined to the nucleus have an intermediate-size CVSC. C-capsids purified from the nuclei of cells infected with the UL34 deletion mutant vRR1072 were icosahedrally reconstructed. Superimposed maps are shown between the vRR1072 map and those of a B-capsid (A) and cytoplasmic C-capsids of ARΔUL36 (B), the WT (C), and FRΔUL37 (D). The B-capsid and ARΔUL36 maps are shown in gray in panels A and B, respectively, while the vRR1072 map is shown in gray in panels C and D. The excess densities that are shown radially colored belong to vRR1072 (A and B), the WT (C), and FRΔUL37 (D). The locations of the penton (5), a peripentonal hexon (P), and a Ta and Tc triplex are marked on panel A. Each black arrowhead indicates the position of one CVSC density. Scale bar = 50 Å.